Inhibitory effects of Sanghwang mushrooms, Phellinus linteus strains and Phellinus baumii, on platelet aggregation

Hee-Wan Kang^1,2^*, Man-Hee Rhee³, Woon-Hyung Yeo⁴

¹Department of Horticultural Life Science, Hankyong National University, Ansung 17579, Korea
²Institute of Genetic Engineering, Hankyong National University, Anseong 17579, Korea
³College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Korea
⁴KT&G Central Research Institute, Daejeon 34128, Korea

*Corresponding author
E-mail : kanghw2@hknu.ac.kr
Tel : +82-31-670-5420, Fax : +82-31-676-2602

Abstract

The fruiting bodies of Sanghwang mushrooms, Phellinus linteus HN1009K (PLH) and Phellinus linteus (Korea Sanghwang, PLK), and Phellinus baumii (Jangsu Sangwhang, PB), were extracted with 70% methanol. The methanolic extracts of different concentrations (5–200 μg/ml) showed inhibitory effects of 20–95% on plated aggregation induced by collagen (2.5 ug/ml), ADP (10 uM), and thrombin (0.1 U/ml). The PLH, PLK, and PB extracts (200 ug/ml) reduced ATP release from ADP-activated platelets by 50¬60%. These results suggest that the methanolic extracts from Sanghwang mushrooms inhibit platelet aggregation.

상황버섯, Phellinus linteus 계통과 Phellinus baumii 의 항 혈소판 응집 효과

강희완^1,2^*, 이만휘³, 여운형⁴

¹한경대학교원예생명과학과
²한경대학교유전공학연구소
³경북대학교 수의과대학
⁴케이티엔지 R&D 본부

Inhibitory effects of Sanghwang mushrooms, Phellinus linteus strains and Phellinus baumii, on platelet aggregation

Abstract

상황버섯, Phellinus linteus 계통과 Phellinus baumii 의 항 혈소판 응집 효과

초록

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