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ISSN : 1738-0294(Print)
ISSN : 2288-8853(Online)
Journal of Mushrooms Vol.15 No.3 pp.124-128

Inhibitory effects of Sanghwang mushrooms, Phellinus linteus strains and Phellinus baumii, on platelet aggregation

Hee-Wan Kang1,2*, Man-Hee Rhee3, Woon-Hyung Yeo4
1Department of Horticultural Life Science, Hankyong National University, Ansung 17579, Korea
2Institute of Genetic Engineering, Hankyong National University, Anseong 17579, Korea
3College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Korea
4KT&G Central Research Institute, Daejeon 34128, Korea
*Corresponding author
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The fruiting bodies of Sanghwang mushrooms, Phellinus linteus HN1009K (PLH) and Phellinus linteus (Korea Sanghwang, PLK), and Phellinus baumii (Jangsu Sangwhang, PB), were extracted with 70% methanol. The methanolic extracts of different concentrations (5–200 μg/ml) showed inhibitory effects of 20–95% on plated aggregation induced by collagen (2.5 ug/ml), ADP (10 uM), and thrombin (0.1 U/ml). The PLH, PLK, and PB extracts (200 ug/ml) reduced ATP release from ADP-activated platelets by 50¬60%. These results suggest that the methanolic extracts from Sanghwang mushrooms inhibit platelet aggregation.

상황버섯, Phellinus linteus 계통과 Phellinus baumii 의 항 혈소판 응집 효과

강희완1,2*, 이만휘3, 여운형4
3경북대학교 수의과대학
4케이티엔지 R&D 본부